| Date | Location | Result | |
| Nov 12, 2016 | Detroit, Mich. | Grand Valley State 24, Wayne State 21 | Box score |
| Nov 05, 2016 | Columbus, Ohio | Ohio Dominican 28, Wayne State 17 | Box score |
| Oct 29, 2016 | Big Rapids, Mich. | Ferris State 42, Wayne State 20 | Box score |
| Oct 22, 2016 | Detroit, Mich. | Wayne State 42, Saginaw Valley 14 | Box score |
| Oct 15, 2016 | Detroit, Mich. | Wayne State 47, Walsh 14 | Box score |
| Oct 08, 2016 | Findlay, Ohio | Wayne State 37, Findlay 21 | Box score |
| Oct 01, 2016 | Detroit, Mich. | Wayne State 41, Hillsdale 30 | Box score |
| Sep 24, 2016 | Detroit, Mich. | Wayne State 35, Tiffin 21 | Box score |
| Sep 17, 2016 | Detroit, Mich. | Wayne State 50, Lake Erie 7 | Box score |
| Sep 10, 2016 | Ashland, Ohio | Ashland 36, Wayne State 25 | Box score |
| Sep 03, 2016 | Midland, Mich. | Wayne State 28, Northwood 3 | Box score |