| Date | Location | Result | |
| Nov 12, 2022 | Detroit, Michigan | Ferris St. 40, Wayne State 14 | Box score |
| Nov 05, 2022 | Allendale, Mich. | Grand Valley State 42, Wayne State 14 | Box score |
| Oct 22, 2022 | Detroit, Michigan | Saginaw Valley 21, Wayne State 14 | Box score |
| Oct 15, 2022 | Caledonia, Michigan | Davenport 47, Wayne State 43 | Box score |
| Oct 08, 2022 | Houghton, Michigan | Michigan Tech 35, Wayne State 34 | Box score |
| Oct 01, 2022 | Detroit, Michigan | Northern Mich. 37, Wayne State 30 | Box score |
| Sep 24, 2022 | Detroit, Michigan | Grand Valley St. 48, Wayne State 9 | Box score |
| Sep 17, 2022 | Detroit, Michigan | Wis.-La Crosse 28, Wayne State 21 | Box score |
| Sep 10, 2022 | Detroit, Michigan | Wayne State 30, Shaw 22 | Box score |
| Sep 03, 2022 | Slippery Rock, Pa. | Slippery Rock 42, Wayne State 10 | Box score |