| Date | Location | Result | |
| 03/13/21 | Evansville, Ind. (Ford Center) | Ashland 76, Wayne State 61 | Box score |
| 03/04/21 | Hammond, Ind. | Saginaw Valley 76, Wayne State 74 | Box score |
| 02/27/21 | Detroit, Mich. (Matthaei) | Wayne State 70, Ferris St. 68 | Box score |
| 02/26/21 | Detroit, Mich. (Matthaei) | Ferris St. 84, Wayne State 71 | Box score |
| 02/20/21 | Detroit, Mich. (Matthaei) | Wayne State 86, Saginaw Valley 67 | Box score |
| 02/19/21 | Detroit, Mich. (Matthaei) | Wayne State 80, Saginaw Valley 65 | Box score |
| 02/16/21 | Ashland, Ohio | Wayne State 64, Ashland 60 | Box score |
| 02/13/21 | Kenosha, Wis. | Wayne State 63, Wis.-Parkside 60 | Box score |
| 02/12/21 | Kenosha, Wis. | Wis.-Parkside 68, Wayne State 64 | Box score |
| 02/09/21 | Allendale, Mich. (GVSU Fieldhouse) | Wayne State 62, Grand Valley St. 59 | Box score |
| 02/06/21 | Detroit, Mich. (Matthaei) | Wayne State 92, Purdue Northwest 89 | Box score |
| 02/05/21 | Detroit, Mich. (Matthaei) | Wayne State 72, Purdue Northwest 56 | Box score |
| 01/26/21 | Detroit, Mich. (Matthaei) | Wayne State 58, Ashland 50 | Box score |
| 01/23/21 | Midland, Mich. - Riepma Arena | Northwood 67, Wayne State 66 | Box score |
| 01/22/21 | Midland, Mich. - Riepma Arena | Northwood 74, Wayne State 67 | Box score |
| 01/16/21 | Detroit, Mich. (Matthaei) | Wayne State 88, Davenport 75 | Box score |
| 01/15/21 | Detroit, Mich. (Matthaei) | Wayne State 86, Davenport 68 | Box score |
| 01/09/21 | Sault Ste. Marie, MI | Lake Superior St. 75, Wayne State 64 | Box score |
| 01/08/21 | Sault Ste. Marie, MI | Wayne State 87, Lake Superior St. 76 | Box score |