| Singles competition |
| 1. #30 Anais Ruyssen (WSUW) def. Vasileia Griva (GV-W) 6-2, 6-3 |
| 2. Taylor Barrett (GV-W) def. Marta Komar (WSUW) 7-5, 6-4 |
| 3. Malak Arafat (WSUW) def. Rachel Sam (GV-W) 7-6 (7-3), 5-7, 6-0 |
| 4. Dea Gorgidze (WSUW) def. Anna Soteras (GV-W) 6-3, 1-6, 6-1 |
| 5. Martyna Szpakowska (WSUW) vs. Estefania Hernandez (GV-W) 6-4, unfinished |
| 6. Shanice Weekes (WSUW) vs. Amanda Diaz (GV-W) 6-0, unfinished |
| Doubles competition |
| 1. #14 Anais Ruyssen/Marta Komar (WSUW) def. #12 Vasileia Griva/Taylor Barrett (GV-W) 6-1 |
| 2. Malak Arafat/Dea Gorgidze (WSUW) vs. Estefania Hernandez/Rachel Sam (GV-W) 3-4, unfinished |
| 3. Martyna Szpakowska/Shanice Weekes (WSUW) def. Ana Romero Gonzalez/Amanda Diaz (GV-W) 6-2 |
| Match Notes |
| Grand Valley State 16-7; National ranking #21; Regional ranking #3 |
| Wayne State 23-3; National ranking #7; Regional ranking #2 |
| Order of finish: Doubles (1,3); Singles (1,2,4,3) |
| 2023 NCAA Midwest Regionals |
| Hosted by Wayne State University. |
| Wayne State was the 2 seed and Grand Valley State the 3 seed. |