| Date | Results | |
| 04/25/2021 | Wayne State Mens Tennis 4, Purdue Northwest 1 | |
| 04/24/2021 | Grand Valley State 4, Wayne State Mens Tennis 0 | |
| 04/23/2021 | Wayne State Mens Tennis 4, Davenport 0 | |
| 04/20/2021 | Dayton 5, Wayne State Mens Tennis 2 | |
| 04/17/2021 | Wayne State Mens Tennis 6, Northwood 1 | |
| 04/12/2021 | Wayne State Mens Tennis 6, Lake Superior State 1 | |
| 04/11/2021 | Wayne State Mens Tennis 7, Michigan Tech 0 | |
| 04/09/2021 | Wayne State Mens Tennis 5, Ashland 2 | |
| 03/26/2021 | Wayne State Mens Tennis 7, Davenport 0 | |
| 03/20/2021 | Grand Valley State 5, Wayne State 2 | |
| 03/19/2021 | Ferris State 4, Wayne State 3 | |
| 03/16/2021 | Findlay 4, Wayne State Mens Tennis 3 | |
| 02/28/2021 | Wayne State Mens Tennis 6, Tiffin University 1 | |
| 02/24/2021 | Western Michigan Men's 7, Wayne State University 0 | |
| 02/21/2021 | Hillsdale College 4, Wayne State 3 | |
| 02/19/2021 | Northwestern Ohio 5, Wayne State 4 | |